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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL4
All Species:
21.82
Human Site:
Y453
Identified Species:
34.29
UniProt:
Q8WUA2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA2
NP_624311.1
492
57225
Y453
S
R
E
R
D
G
H
Y
S
N
S
H
K
S
K
Chimpanzee
Pan troglodytes
XP_527529
607
69328
Y568
S
R
E
R
D
G
H
Y
S
N
S
H
K
S
K
Rhesus Macaque
Macaca mulatta
XP_001084421
492
57172
Y453
S
R
E
R
D
G
H
Y
S
N
S
H
K
S
K
Dog
Lupus familis
XP_541147
492
57155
Y453
S
R
E
R
D
G
H
Y
S
N
S
H
K
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXG3
492
57212
Y453
S
R
E
R
D
G
H
Y
S
N
S
H
K
P
K
Rat
Rattus norvegicus
NP_001101927
357
40656
V319
H
V
D
F
S
Q
S
V
A
K
V
K
W
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506397
487
56623
H449
S
R
D
T
D
N
R
H
G
Y
S
K
S
K
D
Chicken
Gallus gallus
XP_419663
478
55881
S439
R
S
R
S
Q
E
R
S
Y
S
K
H
K
D
K
Frog
Xenopus laevis
Q6GLX7
477
54856
F431
W
L
S
H
V
L
Q
F
E
E
K
S
G
K
V
Zebra Danio
Brachydanio rerio
NP_001121802
454
52864
S415
K
D
R
S
R
Q
R
S
R
S
R
D
R
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651291
653
75452
E488
R
R
R
S
R
P
R
E
Q
N
E
R
R
R
S
Honey Bee
Apis mellifera
XP_001121334
512
60307
Y446
D
K
S
K
R
E
N
Y
K
E
H
K
Q
K
K
Nematode Worm
Caenorhab. elegans
NP_492343
427
50388
R389
R
R
S
S
D
N
H
R
D
R
D
R
S
Y
R
Sea Urchin
Strong. purpuratus
XP_001192414
536
61906
E493
R
R
K
D
E
R
R
E
K
D
R
D
T
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871A4
494
56481
D450
D
A
D
R
R
R
D
D
R
D
L
D
R
R
D
Conservation
Percent
Protein Identity:
100
80.8
98.7
98.1
N.A.
96.7
71.9
N.A.
77
80.8
23.5
69.7
N.A.
42.4
48.6
47.5
51.1
Protein Similarity:
100
80.8
98.9
98.7
N.A.
98.1
72.3
N.A.
86.1
89
45.7
81
N.A.
55.9
65.8
65.6
65.4
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
26.6
20
0
0
N.A.
13.3
13.3
20
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
40
26.6
6.6
20
N.A.
20
40
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
20
7
47
0
7
7
7
14
7
20
0
7
14
% D
% Glu:
0
0
34
0
7
14
0
14
7
14
7
0
0
7
0
% E
% Phe:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
34
0
0
7
0
0
0
7
7
7
% G
% His:
7
0
0
7
0
0
40
7
0
0
7
40
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
7
7
7
0
0
0
0
14
7
14
20
40
27
47
% K
% Leu:
0
7
0
0
0
7
0
0
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
14
7
0
0
40
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
7
14
7
0
7
0
0
0
7
0
0
% Q
% Arg:
27
60
20
40
27
14
34
7
14
7
14
14
20
14
20
% R
% Ser:
40
7
20
27
7
0
7
14
34
14
40
7
14
27
7
% S
% Thr:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
7
0
0
7
0
0
7
0
0
7
0
0
0
7
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
7
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _